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All through meiotic prophase I, after telomere attachment into the INM, phosphorylation of TERB1 triggers a phenomenon often known as telomere cap Trade [37]. Throughout this process, the shelterin sophisticated seems to generally be temporarily displaced from the telomeric DNA, and replaced by meiotic proteins TERB1, TERB2, and MAJIN. Cap exchange
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Manhattan plot of altered log10 (P values) for all phecodes evaluating their incidence per SD telomere shortening. Highlighted are associations results with ?log10 P values amongst ten and a hundred and twenty.Steady analysis initiatives devoted to evolving neuromodulation methods and detailing underlying mechanisms hold the prospect of broader use